Emulsifier-free finely disperse systems of the water-in-oil type

ABSTRACT

Cosmetic or dermatological preparations which are finely disperse systems of the water-in-oil type, comprising 
     1. an oil phase, 
     2. a water phase, 
     3. a combination of 
     a) at least one modified phyllosilicate 
     b) and boron nitride, where both the modified phyllosilicate or phyllosilicates and the boron nitride exhibit both hydrophilic and lipophilic properties, i.e. have amphiphilic character and position themselves at the water/oil interface and 
     4. at most 0.5% by weight of one or more emulsifiers and 
     optionally comprising further cosmetic or pharmaceutical auxiliaries, additives and/or active ingredients.

The present invention relates to emulsifier-free finely disperse systemsof the water-in-oil type, preferably as cosmetic or dermatologicalpreparations.

By far the most important type of product in the field of skin carecompositions are emulsions. Emulsions are disperse two- or multi-phasesystems, cosmetic emulsions consisting of at least one fatty phase (fatsand mineral oils, fatty acid esters etc.) and at least one water phase(water, glycerol, glycols etc.), which are finely distributed in oneanother with the help of emulsifiers. The lipophilic phase of a bodycare emulsion usually comprises a mixture of oils, fats and waxes, thecomposition of which is said to significantly influence theproduct-determining properties such as skin care and feel on the skin.

If the two liquids are water and oil and if oil droplets are finelydistributed in water, then this is an oil-in-water emulsion (O/Wemulsion, e.g. milk). The basic character of an O/W emulsion isdetermined by the water. In the case of a water-in-oil emulsion (W/Oemulsion, e.g. butter), the principle is reversed, the basic characterhere being determined by the oil.

In order to achieve permanent dispersion of one liquid in another,emulsions in the traditional sense require the addition of asurface-active substance (emulsifier). Emulsifiers have an amphiphilicmolecular structure, consisting of a polar (hydrophilic) and a nonpolar(lipophilic) molecular moiety, which are spatially separate from oneanother. They lower the surface tension between the phases bypositioning themselves at the interface between two liquids (they forminterfacial films), as a result of which irreversible coalescence of thedroplets is prevented. Emulsions are frequently stabilized usingemulsifier mixtures.

Traditional emulsifiers can, depending on their hydrophilic molecularmoiety, be divided into ionic (anionic, cationic and amphoteric) andnonionic:

The most well-known example of an anionic emulsifier is soap, which isusually the term used for the water-soluble sodium or potassium salts ofsaturated and unsaturated higher fatty acids.

Important examples of cationic emulsifiers are the quaternary ammoniumcompounds.

The hydrophilic molecular moiety of nonionic emulsifiers frequentlyconsists of glycerol, polyglycerol, sorbitans, carbohydrates andpolyoxyethylene glycols and, in most cases, is linked to the lipophilicmolecular moiety via ester and ether bonds. The lipophilic molecularmoiety usually consists of fatty alcohols, fatty acids or isofattyacids.

By varying the structure and the size of the polar and nonpolarmolecular moiety, the lipophilicity and hydrophilicity of emulsifierscan be varied within wide limits.

A decisive factor for the stability of an emulsion is the correct choiceof emulsifiers. In this connection, the characteristics of all thesubstances present in the system are to be taken into consideration. Inthe case of, for example, skin care emulsions, polar oil components and,for example, UV filters lead to instability. As well as the emulsifiers,therefore, other stabilizers are also used which, for example, increasethe viscosity of the emulsion and/or act as protective colloid.

Cosmetic preparations are essentially used for skin care. The main aimof skin care in the cosmetics sense is to strengthen or rebuild theskin's natural function as the barrier against environmental influences(e.g. dirt, chemicals, microorganisms) and against the loss ofendogenous substances (e.g. water, natural fats, electrolytes). If thisfunction becomes impaired, increased resorption of toxic or allergenicsubstances or attack by microorganisms may result, leading to toxic orallergic skin reactions.

Another aim of skin care is to compensate for the loss by the skin oflipids and water caused by daily washing. This is particularly importantwhere the natural regeneration ability is inadequate. Furthermore,skincare products should protect against environmental influences, inparticular against sun and wind, and delay skin ageing.

The harmful effect of the ultraviolet part of solar radiation on theskin is generally known. Depending on their respective wavelength, therays have different effects on the skin organ: UV-C radiation having awavelength of less than 290 nm is absorbed by the ozone layer in theearth's atmosphere and is of no physiological importance. By contrast,rays in the range between 290 nm and 320 nm, the UV-B region, causeerythema, simple sunburn or even burns of varying severity. UV-Aradiation (320 to 400 nm) is much more harmful than UV-B radiation withregard to the triggering of photodynamic, specifically phototoxic,reactions and chronic changes in the skin. For example, UV-A radiationon its own under very normal everyday conditions is sufficient to damagecollagen and elastin fibres within a short period. The harmful effect ofUV-B radiation can also be further intensified by UV-A radiation.

In addition, even very low doses of radiation can trigger photochemicalreactions. These include, in particular, the formation of free radicals,which in turn can trigger uncontrolled secondary reactions as a resultof their high reactivity. In order to prevent such reactions, as well asUV filter substances, it is also possible to additionally addantioxidants and/or free-radical scavengers to cosmetic ordermatological formulations.

Emulsions also play the decisive role in the field of sunscreenformulations. In this connection, preference is given to flowableemulsions, since they can be applied more easily than viscous creams.Most sunscreens are applied in the vicinity of water or during sportingactivity (perspiration), for which reason the water resistance of suchformulations is to be attributed particular importance. Awater-resistant sunscreen protects the user not only after bathing, butalso protects him against sunburn during bathing.

In order to achieve high sunscreen factors coupled with very good waterresistance, W/O formulations are advantageous. However, W/O emulsions ofthe prior art frequently have unsatisfactory cosmetic properties. Duringapplication, appropriate preparations can leave behind a greasy, shinyand sometimes sticky impression on the skin and—particularly on hairyskin—are difficult to spread. In individual cases, therefore, suchpreparations may not even be marketable since they are unacceptable toor viewed negatively by the consumer.

An object of the present invention was therefore to remedy thedisadvantages of the prior art and to find preparations of thewater-in-oil type which, for example, permit the formulation of highsunscreen factors coupled with very good water resistance, but which donot leave behind a greasy or sticky impression on the skin.

In addition, cosmetic preparations are also used as deodorants. Suchformulations are used to control body odour which forms when freshperspiration, which is in itself odourless, is decomposed bymicroorganisms.

Medicinal topical compositions usually comprise one or more medicamentsin an effective concentration. For the sake of simplicity, in order todistinguish clearly between cosmetic and medicinal use and correspondingproducts, reference is made to the legal provisions of the FederalRepublic of Germany (e.g. Cosmetics Directive, Food and Drugs Act).

The use of customary emulsifiers in cosmetic or dermatologicalpreparations is in itself acceptable. Nevertheless, emulsifiers, likeultimately any chemical substance, may in individual instances causeallergic reactions or reactions based on oversensitivity of the user.

For example, it is known that certain light dermatoses are triggered bycertain emulsifiers, but also by various fats and simultaneous exposureto sunlight. Such light dermatoses are also called “Mallorca acne”.There has thus been no lack of attempts to reduce the amount ofcustomary emulsifiers to a minimum, and in an ideal case evencompletely.

A reduction in the required amount of emulsifier can, for example, beachieved by taking advantage of the fact that very finely divided solidparticles have an additional stabilizing action on an emulsion. Thisresults in an accumulation of the solid substance at the oil/water phaseboundary in the form of a layer, as a result of which coalescence of thedisperse phases is prevented. Of fundamental importance here are not thechemical properties, but the surface properties of the solid particles.

A relatively new technical development involves stabilizing cosmetic ordermatological preparations only using very finely divided solidparticles. Such “emulsifier-free” emulsions are also referred to asPickering emulsions after their inventor.

Basic experiments have shown that one characteristic of a Pickeringemulsion is that the solid particles are arranged at the interfacebetween the two liquid phases, where they form, as it were, a mechanicalbarrier against the combining of the liquid droplets.

One way of achieving solid stabilization in a cosmetic or dermatologicalpreparation, according to May-Alert (Pharmazie in unserer Zeit [Pharmacyin our Time], Vol. 15. 1986, No. 1, 1-7) for example, is to useemulsifier mixtures which comprise both anionic and cationicsurfactants. Since mixing anionic and cationic surfactants alwaysresults in the precipitation of insoluble, electroneutral compounds,deliberate precipitation of these neutral surfactants in the oil/waterinterface makes it possible to achieve additional solids stabilizationin the sense of a Pickering emulsion.

In addition, the WO Specification WO-98/42301 describes emulsifier-freefinely disperse systems of the water-in-oil type which are stabilized bythe addition of micronized inorganic pigments from the group of metaloxides.

However, the prior art was unable to point the way to the presentinvention.

A further object of the present invention was therefore to developcosmetic and dermatological bases for cosmetic and dermatologicalpreparations which are characterized by good skin compatibility.

It was also an object of the present invention to provide products withthe widest possible variety of applications. For example, the intentionwas to provide bases for preparation forms such as cleansing emulsions,face care and body care preparations or deodorants and, in particular,light protection agents, and also, for example, preparations againstacne and other skin conditions.

A further object of the present invention was to enrich the prior artwith cosmetic or dermatological preparations in which any use ofemulsifiers of the traditional type can be dispensed with.

Surprisingly, all of these objects are achieved by cosmetic ordermatological preparations which are finely disperse systems of thewater-in-oil type, comprising

1. an oil phase,

2. a water phase,

3. a combination of

a) at least one modified phyllosilicate

b) and boron nitride, where both the modified phyllosilicate orphyllosilicates and the boron nitride exhibit both hydrophilic andlipophilic properties, i.e. have amphiphilic character and positionthemselves at the water/oil interface and

4. at most 0.5% by weight of one or more emulsifiers and

optionally comprising further cosmetic or pharmaceutical auxiliaries,additives and/or active ingredients.

According to the invention, it is particularly advantageous if thepreparations comprise significantly less than 0.5% by weight of one ormore emulsifiers. Very particular preference is given to preparationsaccording to the invention which are entirely free from emulsifiers inthe traditional sense.

The preparations according to the invention are mixtures of oils oroil-soluble substances and water or water-soluble components, which arestabilized by the addition of the combination according to the inventionand do not have to comprise an emulsifier in the traditional sense.

The preparations according to the invention are entirely satisfactorypreparations in every respect which, surprisingly, have excellentcosmetic properties, do not leave behind a greasy or sticky impressionon the skin, and are characterized by excellent skin compatibility.

Silicates are salts and esters (silicic esters) of orthosilicic acid[Si(OH)₄] and condensation products thereof. Silicates are not only theclass of minerals which contain the most types, but are also extremelyimportant from a geological and industrial viewpoint. Over 80% of theearth's crust consists of silicates. Phyllosilicates are (ideally)silicate structures having two-dimensionally infinite layers of [SiO₄]⁴⁻tetrahedra, each tetrahedron being bonded to neighbouring tetrahedra by3 bridging oxygens.

Only approximate chemical formulae can be given for phyllosilicatessince they have a large ion-exchange capability, and silicon can bereplaced by aluminium, and this in turn can be replaced by magnesium,Fe²⁺, Fe³⁺, Zn and the like. The negative charge of the layers which mayresult is usually balanced by cations, in particular by Na⁺ and Ca²⁺ ininterlayer positions.

Phyllosilicates can swell by reversible intercalation of water (in a 2-to 7-fold amount) and other substances, such as, for example, alcohols,glycols and the like. Their use as thickeners in cosmetic compositionsis, accordingly, known per se. However, the prior art was unable topoint the way to the present invention.

Advantageous phyllosilicates which can be used in a combinationaccording to the invention with boron nitride are, for example, thosewhose greatest expansion direction in the unmodified and unswollen statehas, on average, a length of less than 10 μm. For example, the averageexpansions of the modified phyllosilicate particles used can be 1000nm×100 nm×1 nm and below. The effective size of the modifiedphyllosilicate particles in a cosmetic or dermatological formulationnaturally depends on the amount of intercalated substances.

Advantageous modified phyllosilicates for the purposes of the presentinvention are, for example, modified smectites.

Smectites are always very finely particulate (in most cases<2 mm)three-layer clay minerals (2:1 phyllosilicates) which occur mainly aslamella-shaped, moss-like or spherical aggregates, in which a centrallayer of octahedrally coordinated cations is sandwiched by two layers of[(Si,Al)O₄] tetrahedra. Smectites are described in an idealized mannerby the following structural formula, in which circles filled in whiterepresent silicon and/or aluminium atoms, circles filled in pale greyare oxygen atoms, circles filled in dark grey are hydrogen atoms, andcircles filled in black are aluminium, magnesium, iron atoms and/orother exchange cations:

Advantageous modified smectites are, for example, modifiedmontmorillonites. Montmorillonites are described by the approximatedchemical formula Al₂[(OH)₂/Si₄O₁₀].n H₂O or Al₂O₃.4SiO₂.H₂O.n H₂O, andare clay minerals belonging to the dioctahedral smectites.

Also particularly advantageous for the purposes of the present inventionare, for example, modified hectorites. Hectorites are types of smectitesand have the approximate chemical formula M⁺_(0.3)(Mg_(2.7)Li_(0.3))[Si₄O₁₀(OH)₂], in which M⁺ is in most cases Na⁺.

Also advantageous for the purposes of the present invention are modifiedbentonites. Bentonites are clays and rocks which contain smectites,especially montmorillonite, as main minerals. The “crude” bentonites areeither calcium bentonites (referred to in Great Britain as fuller'searths) or sodium bentonites (also: Wyoming bentonites).

Modified phyllosilicates for the purposes of the present invention arephyllosilicates, in particular the phyllosilicate types alreadymentioned, whose organophilicity (also: lipophilicity) has beenincreased, for example by reaction with quaternary ammonium compounds.Such phyllosilicates are also referred to as organophillicphyllosilicates.

Particularly advantageous for the purposes of the present invention arebentones, i.e. organic derivatives of montmorillonites (or bentonites)and/or hectorites, which are prepared by ion-exchange reactions withalkylammonium bases.

Advantageous modified phyllosilicates for the purposes of the presentinvention are obtainable, for example, by reacting phyllosilicates withquaternium-18. Quaternium-18 is a mixture of quaternary ammoniumchloride salts which are described by the following structural formula:

in which

the radicals R¹ are independently of one another chosen from the groupconsisting of methyl and hydrogenated tallow radicals having a chainlength of from 12 to 20 carbon atoms.

According to the invention, particular preference is given tostearalkonium hectorite, a reaction product of hectorite andstearalkonium chloride (benzyldimethylstearyl-ammonium chloride), andquaternium-18 hectorite, a reaction product of hectorite andquaternium-18, which are available, for example, under the trade namesBentone 27 and Bentone 38 from Nordmann & Rassmann.

The total amount of one or more modified phyllosilicates in the finishedcosmetic or dermatological preparations is advantageously chosen fromthe range 0.05 to 5.0% by weight, preferably 0.1 to 1.0% by weight,based on the total weight of the preparations.

Advantageous boron nitrides which can be used in a combination accordingto the invention with one or more modified phyllosilicates are, forexample, the boron nitrides listed below:

Trade name Obtainable from Boron Nitride Powder Advanced Ceramics BoronNitride Powder Sintec Keramik Ceram Blanche Kawasaki HCST Boron NitrideStark Très BN ® Carborundum Wacker-Bornitrid BNP Wacker-Chemie

It is advantageous to choose the average particle diameter of the boronnitride particles used to be less than 20 μm, particularlyadvantageously less than 15 μm.

Pickering emulsions for the purposes of the present invention arelikewise advantageously stabilized by combinations of one or moremodified phyllosilicates with boron nitride particles which have beensurface-treated (“coated”) to repel water, the intention being for theamphiphilic character to be simultaneously formed or retained.

An advantageous coating of the boron nitride particles consists ofdimethylpolysiloxane (also: dimethicone), a mixture of completelymethylated, linear siloxane polymers which have been terminally blockedwith trimethylsiloxy units. The boron nitride particles treated withdimethicone and obtainable from Carborundum under the trade name TrèsBN® UHP 1106, for example, are advantageous.

Also advantageous is a coating of the boron nitride particles withpolymethylhydrogen-siloxane, a linear polysiloxane, which is alsoreferred to as methicone. Advantageous boron particles coated withmethicone are, for example, those obtainable from Carborundum under thetrade name Très BN® UHP 1107.

The total amount of boron nitride (one or more compounds) in thefinished cosmetic or dermatological preparations is advantageouslychosen from the range 0.1 to 5.0% by weight, preferably 0.5 to 2.0% byweight, based on the total weight of the preparations.

Although it is particularly preferred to stabilize the preparationsaccording to the invention only by the addition of the combinationaccording to the invention, it may also be advantageous to use furtheramphiphilic pigments which may also contribute to the stabilization ofthe Pickering emulsions.

Such pigments are, for example, micronized, inorganic pigments chosenfrom the group of amphiphilic metal oxides, in particular from the groupconsisting of titanium dioxide, zinc oxide, silicon dioxide andsilicates (e.g. talc), it being possible for the metal oxides to bepresent individually or as a mixture. In this connection, it isessentially unimportant in which of the potentially naturally occurringmodifications the amphiphilic metal oxides used are present.

It is advantageous to choose the average particle diameter of thesepigments to be between 1 nm and 200 nm, particularly advantageouslybetween 5 nm and 100 nm.

For the purposes of the present invention, it is advantageous to use, aswell as the combination according to the invention, untreated, virtuallypure pigment particles, in particular those which can also be used asdye in the foods industry and/or as absorbers of UV radiation insunscreens. Advantageous examples are the zinc oxide pigments availablefrom Merck, and those available under the trade names Zinkoxid neutralfrom Haarmann & Reimer or NanoX from Harcros Chemical Group.

According to the invention it is also advantageous to use inorganicpigments which have been surface-treated (“coated”) to repel water, theintention being for the amphiphilic character of these pigments to beformed or retained at the same time. This surface treatment may involveproviding the pigments with a thin hydrophobic layer by methods knownper se.

Such a process, which is described below using titanium dioxide as anexample, consists, for example, in producing the hydrophobic surfacelayer by a reaction in accordance with

nTiO₂ +m(RO)₃Si—R′→nTiO₂(surf.)

n and m are stoichiometric parameters to be used as desired, and R andR′ are the desired organic radicals. Particularly advantageous TiO₂pigments are, for example, those coated with aluminium stearate andobtainable under the trade name MT 100 T from TAYCA.

A further advantageous coating of the additional pigments consists ofdimethylpolysiloxane (also: dimethicone), a mixture of completelymethylated, linear siloxane polymers which have been terminally blockedwith trimethylsiloxy units. Other pigments which are particularlyadvantageous for the purposes of the present invention are zinc oxidepigments which have been coated in this manner.

It also advantageous if the inorganic pigments used in addition to thecombination according to the invention have been coated with a mixtureof dimethylpolysiloxane, in particular dimethylpolysiloxane having anaverage chain length of from 200 to 350 dimethylsiloxane units, andsilica gel, which is also referred to as simethicone. It is particularlyadvantageous if the inorganic pigments have been additionally coatedwith aluminium hydroxide or hydrated aluminium oxide (also: alumina, CASNo.: 1333-84-2). Particularly advantageous combination partners aretitanium dioxides which have been coated with simethicone and alumina,it also be possible for the coating to comprise water. One examplethereof is the titanium dioxide available under the trade name EusolexT2000 from Merck.

It is also advantageous for the purposes of the present invention touse, in addition to the combination according to the invention, amixture of different inorganic, amphiphilic pigment types, eithermixtures within a crystal, for example as iron mixed oxide or talc(magnesium silicate) or else mixtures of two or more types of metaloxide within a preparation. Magnesium silicates are particularlyadvantageous, for example those available under the trade name TalkumMicron from Grolmann.

The combination according to the invention can also advantageously becombined, for example, with titanium dioxide pigments which have beencoated with octylsilanol, and/or with silicon dioxide particles whichhave been surface-treated to repel water. Suitable silicon dioxideparticles are, for example, spherical polyalkylsilsesquioxane particles,as mentioned in European Laid-Open Specification 0 686 391. Suchpolyalkylsilsesquioxane particles are available, for example, under thetrade names Aerosil R972 and Aerosil 200 V from Degussa.

It is further advantageous if, in addition to the combination accordingto the invention, microfine polymer particles are used which are in thepreparation in the form of solids. Favourable examples for the purposesof the present invention are polycarbonates, polyethers, polyethylene,polypropylene, polyvinyl chloride, polystyrene, polyamides,polyacrylates and the like.

According to the invention, microfine polyamide particles, in particularthose available under the trade name SP-500 from TORAY, for example, aresuitable. Also advantageous are polyamide 6 (also: nylon 6) andpolyamide 12- (also: nylon 12) particles. Polyamide 6 is the polyamide[poly(ε-caprolactam)], built up from ε-aminocaproic acid(6-aminohexanoic acid) or ε-caprolactam, and polyamide 12 is apoly(ε-laurolactam) of ε-laurolactam. Advantageous examples for thepurposes of the present invention are Orgasol® 1002 (polyamide 6) andOrgasole® 2002 (polyamide 12) from ELF ATOCHEM.

Further microfine polymer particles which can be used advantageously inaddition to the combination according to the invention are microfinepolymethacrylates. Such particles are available, for example, under thetrade name POLYTRAP® from DOW CHEMICAL.

It is particularly advantageous, although not obligatory, if the furthermicrofine polymer particles have been surface-coated. This surfacetreatment can involve providing the polymer particles with a thinhydrophilic layer by processes known per se. Advantageous coatingsconsist, for example, of titanium dioxide (TiO₂), zirconium dioxide(ZrO₂) or else further polymers, such as, for example, polymethylmethacrylate. Particularly advantageous microfine polymer particles forthe purposes of the present invention are, for example, those availableby the process described in U.S. Pat. No. 4,898,913 for the hydrophiliccoating of hydrophobic polymer particles.

The average particle diameter of the microfine polymer particles used ispreferably chosen to be less than 100 μm, particularly advantageously tobe less than 50 μm. In this connection, it is essentially unimportant inwhich form (platelets, rods, spherules etc.) the polymer particles usedare present.

It is also advantageous if, in addition to the combination according tothe invention, amphiphilic modified polysaccharides are used which donot exhibit thickening properties.

Such amphiphilic polysaccharides are obtainable, for example, byreacting starch with mono-, bi- or polyfunctional reagents or oxidizingagents in reactions which proceed in a predominantly polymer-analogousmanner.

These reactions are based essentially on modifications of the hydroxylgroups of the polyglucans by etherification, esterification or selectiveoxidation. This produces, for example, starch ethers and startch estersof general structural formula

in which R can, for example, be a hydrogen and/or an alkyl and/oraralkyl radical (in the case of starch ethers) or a hydrogen and/or anorganic and/or an inorganic acid radical (in the case of starch esters).Starch ethers and starch esters are advantageous modifiedpolysaccharides for the purposes of the present invention.

In addition to the combination according to the invention, it isparticularly advantageous to use starch ethers, e.g. those obtainable byetherifying starch with tetramethylol-acetylenediurea and which arereferred to as Amylum non mucilaginosum (nonswelling starch).

Also particularly advantageous are starch esters and/or salts thereof,for example sodium and/or aluminium salts of half-esters of starch whichhave low degrees of substitution, in particular sodium starch n-octenylsuccinate of the structural formula (I) in which R is characterized bythe following structure

and which is available, for example, under the trade name Amiogume® 23from CERESTAR, and aluminium starch octenyl succinate, in particularthose available under the trade names Dry Flo® Elite LL and Dry Flo® PCfrom CERESTAR.

It is advantageous to choose the average particle diameter of themodified polysaccharides used together with the combination according tothe invention to be less than 20 μm, particularly advantageously lessthan 15 μm.

The list of given modified polysaccharides which can be combinedadvantageously with the combination according to the invention is not ofcourse intended to be limiting. Modified polysaccharides which areadvantageous further pigments for the purposes of the present inventionare obtainable in numerous ways, either chemical or physical in nature,which are known per se. For the preparation of such polysaccharides,novel ways are in principle also conceivable. In this connection, it isimportant that the modified polysaccharides display amphiphilicproperties and that they do not have a thickening action.

In all of the abovementioned cases it is advantageous to choose theoverall concentration of all further pigments to be greater than 0.05%by weight, particularly advantageously between 0.05% and 30% by weight,based on the total weight of the preparations.

The Pickering emulsions according to the invention can be used as basesfor cosmetic or dermatological formulations. The latter can have thecustomary composition and be used, for example, for the treatment andcare of the skin, as lip care product, as deodorant product and asmake-up or make-up remover product in decorative cosmetics or as a lightprotection preparation. For use, the cosmetic and dermatologicalpreparations according to the invention are applied to the skin in asufficient amount in the manner customary for cosmetics.

Accordingly, for the purposes of the present invention, cosmetics ortopical dermatological compositions can, depending on their composition,be used, for example, as skin protection cream, cleansing milk,sunscreen lotion, nourishing cream, day or night cream etc. In someinstances, it is possible and advantageous to use the compositionsaccording to the invention as bases for pharmaceutical formulations.

The cosmetic and dermatological preparations according to the inventioncan comprise cosmetic auxiliaries, as are customarily used in suchpreparations, e.g. preservatives, bactericides, perfumes, antifoams,dyes, pigments which have a colouring action, thickeners, emollients,moisturizers and/or humectants, fats, oils, waxes or other customaryconstituents of a cosmetic or dermatological formulation, such asalcohols, polyols, polymers, foam stabilizers, electrolytres, organicsolvents or silicone derivatives.

A surprising property of the preparations according to the invention isthat they are very good vehicles for cosmetic or dermatological activeingredients into the skin, advantageous active ingredients beingantioxidants which are able to protect the skin against oxidativestress.

According to the invention, the preparations advantageously comprise oneor more antioxidants. Antioxidants which are favourable, butnevertheless optional, are all antioxidants which are suitable orcustomary for cosmetic and/or dermatological applications. It isadvantageous to use antioxidants as the sole active ingredient classwhen, for example, any cosmetic or dermatological application is at thefore, such as, for example, the control of oxidative stress of the skin.It is, however, also favourable to provide the stick preparationsaccording to the invention with a content of one or more antioxidants ifthe intention is for the preparations to have another purpose, e.g. asdeodorants or sunscreens.

The antioxidants are particularly advantageously chosen from the groupconsisting of amino acids (e.g. glycine, histidine, tyrosine,tryptophan) and derivatives thereof, imidazoles, (e.g. urocanic acid)and derivatives thereof, peptides, such as D,L-carnosine, D-carnosine,L-carnosine and derivatives thereof (e.g. anserine), carotenoids,carotenes (e.g. α-carotene, β-carotene, lycopene) and derivativesthereof, chlorogenic acid and derivatives thereof, lipoic acid andderivatives thereof (e.g. dihydrolipoic acid), aurothioglucose,propylthiouracil and other thiols (e.g. thioredoxin, glutathione,cysteine, cystine, cystamine and the glycosyl, N-acetyl, methyl, ethyl,propyl, amyl, butyl and lauryl, palmitoyl, oleyl, γ-linoleyl,cholesteryl and glyceryl esters thereof) and salts thereof, dilaurylthiodipropionate, distearyl thiodipropionate, thiodipropionic acid andderivatives thereof (esters, ethers, peptides, lipids, nucleotides,nucleosides and salts) and sulphoximine compounds (e.g. buthioninesulphoximines, homocysteine sulphoximine, buthionine sulphones, penta-,hexa-, heptathionine sulphoximines) in very low tolerated doses (e.g.pmol to μmol/kg), and also (metal) chelating agents (e.g. α-hydroxyfattyacids, palmitic acid, phytic acid, lactoferrin), α-hydroxy acids (e.g.citric acid, lactic acid, malic acid), humic acid, bile acid, bileextracts, bilirubin, biliverdin, EDTA, EGTA and derivatives thereof,unsaturated fatty acids and derivatives thereof (e.g. γ-linolenic acid,linoleic acid, oleic acid), folic acid and derivatives thereof,ubiquinone and ubiquinol and derivatives thereof, vitamin C andderivatives (e.g. ascorbyl palmitate, Mg ascorbyl phosphate, ascorbylacetate), tocopherols and derivatives (e.g. vitamin E acetate), vitaminA and derivatives (vitamin A palmitate) and coniferyl benzoate ofbenzoin resin, rutinic acid and derivatives thereof, glycosylrutin,ferulic acid, furfurylideneglucitol, camosine, butylated hydroxytoluene,butylated hydroxyanisole, nordihydroguaiac acid, nordihydroguaiareticacid, trihydroxybutyrophenone, uric acid and derivatives thereof,mannose and derivatives thereof, zinc and derivatives thereof (e.g. ZnO,ZnSO₄), selenium and derivatives thereof (e.g. selenomethionine),stilbenes and derivatives thereof (e.g. stilbene oxide, trans-stilbeneoxide), and the derivatives (salts, esters, ethers, sugars, nucleotides,nucleosides, peptides and lipids) of said active substances which aresuitable according to the invention.

The amount of abovementioned antioxidants (one or more compounds) in thepreparations according to the invention is preferably 0.001 to 30% byweight, particularly preferably 0.05 to 20% by weight, in particular 0.1to 10% by weight, based on the total weight of the preparation.

If vitamin E and/or derivatives thereof are the antioxidant(s), it isadvantageous to choose their respective concentrations from the range0.001 to 10% by weight, based on the total weight of the formulation.

If vitamin A or vitamin A derivatives, or carotenes or derivativesthereof are the antioxidant(s), it is advantageous to choose theirrespective concentrations from the range 0.001 to 10% by weight, basedon the total weight of the formulation.

According to the invention, the active ingredients (one or morecompounds) can also very advantageously be chosen from the group oflipophilic active ingredients, in particular from the following group:

Acetylsalicylic acid, atropine, azulene, hydrocortisone and derivativesthereof, e.g. hydrocortisone-17 valerate, vitamins, e.g. ascorbic acidand derivatives thereof, vitamins of the B and D series, very favourablyvitamin B₁, vitamin B₁₂ and vitamin D₁, but also bisabolol, unsaturatedfatty acids, namely the essential fatty acids (often also called vitaminF), in particular gamma-linolenic acid, oleic acid, eicosapentaenoicacid, docosa-hexaenoic acid and derivatives thereof, chloramphenicol,caffeine, prostaglandins, thymol, camphor, extracts or other products ofa vegetable or animal origin, e.g. evening primrose oil, starflower oilor currant seed oil, fish oils, cod-liver oil or also ceramides andceramide-like compounds and so on.

It is also advantageous to choose the active ingredients from the groupof refatting substances, for example purcellin oil, Eucerit® andNeocerit®.

The list of specified active ingredients or active ingredientcombinations which can be used in the Pickering emulsions according tothe invention should not of course be limiting.

Cosmetic and dermatological preparations which are in the form of asunscreen are also favourable. In addition to the active ingredientcombinations according to the invention, these preferably additionallycomprise at least one UV-A filter substance and/or at least one UV-Bfilter substance. Such formulations can, although it is not necessary,optionally also comprise one or more inorganic pigments as UV filtersubstances.

Inorganic pigments based on metal oxides and/or other metal compoundswhich are insoluble or sparingly soluble in water are preferablypresent, in particular the oxides of titanium (TiO₂), zinc (ZnO), iron(e.g. Fe₂O₃), zirconium (ZrO₂), silicon (SiO₂), manganese (e.g. MnO),aluminium (Al₂O₃), cerium (e.g. Ce₂O₃), mixed oxides of thecorresponding metals, and mixtures of such oxides.

An additional content of stabilizing titanium dioxide and/or zinc oxideparticles can of course also be advantageous, but is not necessary forthe purposes of the present invention.

For the purposes of the present invention, it is also advantageous toprepare cosmetic and dermatological preparations whose main purpose isnot protection against sunlight, but which nevertheless contain UVprotection substances. Thus, for example, UV-A and UV-B filtersubstances are usually incorporated into day creams.

Also, UV protectants, like antioxidants, and if desired, preservatives,provide effective protection of the preparations themselves againstspoilage.

Preparations according to the invention advantageously comprisesubstances which absorb UV radiation in the UV-A and UV-B region, thetotal amount of filter substances being, for example, from 0.1% byweight to 30% by weight, preferably from 0.5 to 20% by weight, inparticular from 1.0 to 15% by weight, based on the total weight of thepreparations, in order to provide cosmetic preparations which protectthe hair and the skin from the entire range of ultraviolet radiation.They can also be used as sunscreens for the hair or the skin.

Advantageous UV-A filter substances for the purposes of the presentinvention are dibenzoyl methane derivatives, in particular4-(tert-butyl)-4′-methoxydibenzoylmethane (CAS No. 70356-09-1), which issold by Givaudan under the name Parsole® 1789 and by Merck under thetrade name Eusolex® 9020.

Further advantageous UV-A filter substances arephenylene-1,4-bis-(2-benzimidazyl)-3,3′-5,5′-tetrasulphonic acid:

and its salts, particularly the corresponding sodium, potassium ortriethanolammonium salts, in particularphenylene-1,4-bis-(2-benzimidazyl)-3,3′-5,5′-tetrasulphonic bis-sodiumsalt:

and 1,4-di(2-oxo-10-sulpho-3-bornylidenemethyl)benzene and salts thereof(in particular the corresponding 10-sulphato compounds, in particularthe corresponding sodium, potassium or triethanolammonium salt), whichis also referred to asbenzene-1,4-di(2-oxo-3-bornylidenemethyl-10-sulphonic acid) and ischaracterized by the following structure:

Advantageous UV filter substances for the purposes of the presentinvention are also broad-band filters, i.e. filter substances whichabsorb both UV-A and also UV-B radiation.

Advantageous broad-band filters and/or UV-B filter substances are, forexample, bisresorcinyltriazine derivates having the following structure:

where R¹, R² and R³ independently of one another are chosen from thegroup of branched and unbranched alkyl groups having 1 to 10 carbonatoms, or are a single hydrogen atom. Particular preference is given to2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine(INCI: Aniso Triazine), which is available under the trade nameTinosorb® S from CIBA-Chemikalien GmbH and to tris(2-ethylhexyl)4,4′,4″-(1,3,5-triazine-2,4,6-triyltriimino)trisbenzoate, synonym:2,4,6-tris[anilino-(p-carbo-2′-ethyl-1′-hexyloxy)]-1,3,5-triazine (INCI:Octyl Triazone), which is marketed by BASF Aktiengesellschaft under thetrade name UVINUL® T 150.

Other UV filter substances, which have the structural formula

are also advantageous UV filter substances for the purposes of thepresent invention, for example the s-triazine derivatives described inEuropean Laid-Open Specification EP 570 838 A1, whose chemical structureis expressed by the generic formula

where

R is a branched or unbranched C₁-C₁₆-alkyl radical, a C₅-C₁₂-cycloalkylradical, optionally substituted with one or more C₁-C₄-alkyl groups,

X is an oxygen atom or an NH group,

R₁ is a branched or unbranched C₁-C₁₈-alkyl radical, a C₅-C₁₂-cycloalkylradical, optionally substituted by one or more C₁-C₄-alkyl groups, or ahydrogen atom, an alkali metal atom, an ammonium group or a group of theformula

in which

A is a branched or unbranched C₁-C₁₈-alkyl radical, a C₅-C₁₂-cycloalkylor aryl radical, optionally substituted by one or more C₁-C₄-alkylgroups,

R₃ is a hydrogen atom or a methyl group,

n is a number from 1 to 10,

R₂ is a branched or unbranched C₁-C₁₈-alkyl radical, a C₅-C₁₂-cycloalkylradical, optionally substituted by one or more C₁-C₄-alkyl groups, whenX is the NH group, and

a branched or unbranched C₁-C₁₈-alkyl radical, a C₅-C₁₂-cycloalkylradical, optionally substituted by one or more C₁-C₄-alkyl groups, or ahydrogen atom, an alkali metal atom, an ammonium group or a group of theformula

in which

A is a branched or unbranched C₁-C₁₈-alkyl radical, a C₅-C₁₂-cycloalkylor aryl radical, optionally substituted by one or more C₁-C₄-alkylgroups,

R₃ is a hydrogen atom or a methyl group,

n is a number from 1 to 10,

when X is an oxygen atom.

A particularly preferred UV filter substance for the purposes of thepresent invention is also an unsymmetrically substituted s-triazine, thechemical structure of which is expressed by the formula

and which is also referred to below as dioctylbutylamidotriazone (INCI:dioctylbutamidotriazone) and is available under the trade name UVASORBHEB from Sigma 3V.

European Laid-Open Specification 775 698 also describes preferredbisresorcinyltriazine derivatives, the chemical structure of which isexpressed by the generic formula

where R₁, R₂ and A₁ represent very different organic radicals.

Also advantageous for the purposes of the present invention are2,4-bis{[4-(3-sulphonato)-2-hydroxypropyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazinesodium salt,2,4-bis{[4-(3-(2-propyloxy)-2-hydroxypropyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine,2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-[4-(2-methoxyethylcarboxyl)phenylamino]-1,3,5-triazine,2,4-bis{[4-(3-(2-propyloxy)-2-hydroxypropyloxy)-2-hydroxy]phenyl}-6-[4-(2-ethylcarboxyl)phenylamino]-1,3,5-triazine,2,4-bis-{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(1-methylpyrrol-2-yl)-1,3,5-triazine,2,4-bis{[4-tris(trimethylsiloxysilylpropyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine,2,4-bis{[4-(2″-methylpropenyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazineand2,4-bis{[4-(1′,1′,1′,3′,5′,5′,5′-heptamethylsiloxy-2″-methylpropyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine.

An advantageous broad-band filter for the purposes of the presentinvention is2,2′-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol),which is characerized by the chemical structural formula

and is available under the trade name Tinosorb® M from CIBA-ChemikalienGmbH.

Another advantageous broad-band filter for the purposes of the presentinvention is2-(2H-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)-oxy]disiloxanyl]propyl]phenol(CAS No.: 155633-54-8) having the INCI name Drometrizole Trisiloxane,which is characterized by the chemical structural formula

The UV-B filters can be oil-soluble or water-soluble. Examples ofadvantageous oil-soluble UV-B filter substances are:

3-benzylidenecamphor derivatives, preferably3-(4-methylbenzylidene)camphor, 3-benzylidenecamphor;

4-aminobenzoic acid derivatives, preferably 2-ethylhexyl4-(dimethylamino)benzoate, amyl 4-(dimethylamino)benzoate;

2,4,6-trianilino(p-carbo-2′-ethyl-1′-hexyloxy)-1,3,5-triazine;

esters of benzalmalonic acid, preferably di(2-ethylhexyl)4-methoxybenzalmalonate,

esters of cinnamic acid, preferably 2-ethylhexyl 4-methoxycinnamate,isopentyl 4-methoxycinnamate;

derivates of benzophenone, preferably 2-hydroxy-4-methoxybenzophenone,2-hydroxy-4-methoxy-4′-methylbenzophenone,2,2′-dihydroxy-4-methoxybenzophenone

and UV filters bonded to polymers.

Examples of advantageous water-soluble UV-B filter substances are:

salts of 2-phenylbenzimidazole-5-sulphonic acid, such as its sodium,potassium or its triethanolammonium salt, and also the sulphonic aciditself;

sulphonic acid derivatives of 3-benzylidenecamphor, such as, forexample, 4-(2-oxo-3-bornylidenemethyl)benzenesulphonic acid,2-methyl-5-(2-oxo-3-bornylidenemethyl)-sulphonic acid and salts thereof.

A further light protection filter substance which can be usedadvantageously according to the invention is ethylhexyl2-cyano-3,3-diphenylacrylate (octocrylene), which is available from BASFunder the name Uvinul® N 539 and is characterized by the followingstructure:

It can also be of considerable advantage to use polymer-bonded orpolymeric UV filter substances in the preparations according to thepresent invention, in particular those described in WO-A-92/20690.

In some instances, it can also be advantageous to incorporate furtherUV-A and/or UV-B filters in accordance with the invention into cosmeticor dermatological preparations, for example certain salicylic acidderivatives, such as 4-isopropylbenzyl salicylate, 2-ethylhexylsalicylate (═octyl salicylate), homomenthyl salicylate.

The list of given UV filters which can be used for the purposes of thepresent invention is not of course intended to be limiting.

Preparations according to the invention can also advantageously be usedas bases for cosmetic deodorants and antiperspirants, so that aparticular embodiment of the present invention relates to Pickeringemulsions as bases for cosmetic deodorants.

Cosmetic deodorants are used to control body odour which forms whenfresh sweat, which is in itself odourless, is decomposed bymicroorganisms. Customary cosmetic deodorants are based on various modesof action.

In antiperspirants, astringents, mainly aluminium salts, such asaluminium hydroxychloride (aluminium chlorohydrate), can reduce sweatformation.

The use of antimicrobial substances in cosmetic deodorants can reducethe bacterial flora of the skin. In an ideal situation, only themicroorganisms which cause the odour would be effectively reduced. Theflow of sweat itself is not influenced as a result, and in idealcircumstances, only microbial decomposition of sweat is stoppedtemporarily.

The combination of astringents and antimicrobial active substances inone and the same composition is also common.

All active ingredients common for deodorants or antiperspirants canadvantageously be used, for example odour concealers, such as customaryperfume constituents, odour-absorbers, for example the phyllosilicatesdescribed in DE 40 09 347, of these in particular montmorillonite,kaolinite, illite, beidellite, nontronite, saponite, hectorite,bentonite, smectite, and also, for example, zinc salts of ricinoleicacid. Antibacterial agents are also suitable to be incorporated into theW/O emulsion sticks according to the invention. Advantageous substancesare, for example, 2,4,4′-trichloro-2′-hydroxy diphenyl ether (Irgasan),1,6-di(4-chlorophenylbiguanido)hexane (chlorhexidine),3,4,4′-trichlorocarbanilide, quaternary ammonium compounds, oil ofcloves, mint oil, thyme oil, triethyl citrate, farnesol(3,7,11-trimethyl-2,6,10-dodecatrien-1-ol) and also the activeingredients or active ingredient combinations described in PatentLaid-Open Specifications DE 37 40 186, DE 39 38 140, DE 42 04 321, DE 4229 707, DE 43 09 372, DE 44 11 664, DE 195 41 967, DE 195 43 695, DE 19543 696, DE 195 47 160, DE 196 02 108, DE 196 02 110, DE 196 02 111, DE196 31 003, DE 196 31 004 and DE 196 34 019, and the patentspecifications DE-42 29 737, DE-42 37 081, DE-43 24 219, DE-44 29 467,DE-44 23 410 and DE-195 16 705. Sodium hydrogencarbonate can also beused advantageously.

The list of specified active ingredients and active ingredientcombinations which can be used the novel Pickering emulsions is ofcourse not intended to be limiting.

The cosmetic deodorants according to the invention can be in the form ofaqueous, cosmetic preparations which can be applied from standardcontainers.

The amount of antiperspirant active ingredients or deodorants (one ormore compounds) in the preparations is preferably from 0.01 to 30% byweight, particularly preferably from 0.1 to 20% by weight, in particular1 to 10% by weight, based on the total weight of the preparation.

The sticks according to the invention are additionally excellentvehicles for dermatological active ingredients. In particular, they aresuitable as carriers for substances effective against acne. Acne is askin disorder with many forms and causes, characterized by noninflamedand inflamed bumps, originating from blocked hair follicles (comedones)which can lead to the formation of pustules, abscesses and scars. Themost frequent is Acne vulgaris, which occurs predominantly in puberty.Causative conditions for Acne vulgaris are the keratinization andblocking of the hair follicle opening, the production of sebum, which isdependent on the level of male sex hormones in the blood, and theproduction of free fatty acids and tissue-damaging enzymes by bacteria(Propionibacterium acnes).

It is therefore advantageous to add to the preparations according to theinvention, substances which are effective against acne, which are, forexample effective against Propionibacterium acnes (for example thosedescribed in DE-A 42 29 707, DE-A 43 05 069, D-A 43 07 976, DE-A 43 37711, DE-A 43 29 379) but also other substances which are effectiveagainst acne, for example all-trans-retinoic acid, 13-cis-retinoic acidand related substances) or antiinflammatory active ingredients, forexample batyl alcohol (α-octadecyl glyceryl ether), selachyl alcohol(α-9-octadecenyl glyceryl ether), chimyl alcohol (α-hexadecyl glycerylether) and/or bisabolol and antibiotics and/or keratolytics.

Keratolytics are substances which soften keratinized skin (such as, forexample, warts, corns, calluses and the like) so that it can be removedmore easily or so that it falls off or peels off.

All of the common substances effective against acne can be usedadvantageously, in particular benzoyl peroxide, bituminosulphonates(ammonium, sodium and calcium salts of shale oil sulphonic acids),salicylic acid (2-hydroxybenzoic acid), miconazole(1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole) andderivatives, adapalene (6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoicacid), azelaic acid (nonanedioic acid), mesulfene(2,7-dimethylthianthrene, C₁₄H₁₂S₂) and aluminium oxide, zinc oxideand/or finely dispersed sulphur.

The amount of antiacne agents (one or more compounds) in thepreparations is preferably from 0.01 to 30% by weight, particularlypreferably 0.1-20% by weight, in particular 1-10% by weight, based onthe total weight of the preparation.

The examples below serve to illustrate the present invention withoutlimiting it. The numerical values in the examples are percentages byweight, based on the total weight of the respective preparations.

EXAMPLES

1 2 3 4 5 6 7 Bentone 38 ® 0.5 1 0.2 0.2 0.5 Bentone 27 ® 0.3 0.7 0.3Boron nitride 0.5 2 1 3 5 1 1 Polyglyceryl-2 dipoly- 0.2 hydroxystearateCetyldimethicone copolyol 0.3 PEG-30 dipolyhydroxy- 0.2 stearateCaprylic/capric triglyceride 10 5 7 Octyldodecanol 10 10 5 Dicaprylylether 5 5 5 5 Cetearyl isononanoate 2 Dimethicone 2 2 5 2 5 5 Mineraloil 5 5 10 5 5 2 Isohexadecane 2 3 5 Hydrogenated 2 3 5 5 polyisobuteneButylene glycol dicapry- 2 5 5 5 8 late/caprate C₁₂₋₁₅ Alkylbenzoate 7 33 5 10 Vitamin E acetate 0.5 0.5 0.5 0.5 0.5 Dioctylbutamidotriazone 3 1Octocrylene 5 6 5 Octyltriazone 1 Methylbenzylidenecamphor 2 4 2 4Butylmethoxydibenzoyl- 2 2 2 methane Titanium dioxide 1 5 4 2 Zinc oxide5 Aerosil R972 ® 0.5 0.5 Preservative 0.5 0.5 0.5 0.5 0.5 0.5 0.5Glycerol 3 5 10 10 5 10 5 MgSO₄ 1 1 NaCl 0.5 1 0.2 1Phenylbenzimidazole- 2 4 sulphonic acid Sodium hydroxide solution, 0.81.3 45% Water ad 100 ad 100 ad 100 ad 100 ad 100 ad 100 ad 100

What is claimed is:
 1. A cosmetic or dermatological preparation, whichpreparation is a finely dispersed water-in-oil system, said preparationcomprising: a) an oil phase; b) a water phase; c) a combination of: i)at least one modified phyllosilicate; and ii) boron nitride; where bothsaid phyllosilicate and said boron nitride have both hydrophilic andlipophilic properties resulting in an amphiphilic character, and bothsaid modified phyllosilicate and said boron nitride position themselvesat an interface of said water phase and said oil phase; d) at most 0.5%by weight of one or more emulsifiers; and e) optionally one or morecosmetic or pharmaceutical auxiliaries, additives and/or activesubstances.
 2. The cosmetic or dermatological preparation according toclaim 1, which is emulsifier-free.
 3. The cosmetic or dermatologicalpreparation according to claim 1, which further comprises a content ofone or more cosmetic or pharmaceutical auxiliaries, additives and/oractive substances.
 4. The cosmetic or dermatological preparationaccording to claim 1, which comprises one or more phyllosilicates in anamount between 0.05 and 5.0% by weight based on the total weight of thepreparation.
 5. The cosmetic or dermatological preparation according toclaim 4, which comprises one or more phyllosilicates in an amountbetween 0.1 and 1.0% by weight based on the total weight of thepreparation.
 6. The cosmetic or dermatological preparation according toclaim 1, which comprises one or more boron nitrides in an amount between0.1 and 5.0% by weight based on the total weight of the preparation. 7.The cosmetic or dermatological preparation according to claim 6, whichcomprises one or more boron nitrides in an amount between 0.5 and 2.0%by weight based on the total weight of the preparation.
 8. The cosmeticor dermatological preparation according to claim 1, which, in additionto the combination of one or more modified phyllosilicates and boronnitride, comprises one or more further pigments.
 9. The cosmetic ordermatological preparation according to claim 8, wherein the one or morefurther pigments are one or more pigments selected from the groupconsisting of modified polysaccharides, microfine polymer particles andmicronized, inorganic pigments.
 10. The cosmetic or dermatologicalpreparation according to claim 9, wherein the micronized, inorganicpigments are selected from the group consisting of amphiphilic metaloxides.
 11. The cosmetic or dermatological preparation according toclaim 10, wherein the amphiphilic metal oxides are selected from thegroup consisting of titanium dioxide, zinc oxide, iron oxides, ironmixed oxides, silicon dioxide, and silicates.
 12. The cosmetic ordermatological preparation according to claim 1, which further comprisesone or more unsymmetrically substituted s-triazine derivatives.
 13. Thecosmetic or dermatological preparation according to claim 12, whichcomprises at least one unsymmetrically substituted s-triazine derivativeselected from the group consisting of2,4-bis-{[4-2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazineand dioctylbutylamidotriazone.
 14. The cosmetic or dermatologicalpreparation according to claim 1, which further comprises one or moresulfonated UV filter substances.
 15. The cosmetic or dermatologicalpreparation according to claim 14, wherein the one or more sulfonated UVfilter substances are selected from the group consisting ofphenylene-1,4-bis(2-benzimidazyl)-3,3′-5,5′-tetrasulfonic acid and saltsthereof, benzene-1,4-di(2-oxo-3-bornylidenemethyl-10-sulfonic acid) andsalts thereof, 2-phenylbenzimidazole-5-sulfonic acid and salts thereof,and sulfonic acid derivatives of 3-benzylidenecanphor and salts thereof.16. The cosmetic or dermatological preparation according to claim 1,which further comprises one or more additives or active substancesselected from the group consisting of antioxidants, astringents,antimicrobially active substances, and substances active against acne.17. A method of caring for skin comprising applying thereto an effectiveamount therefor of a cosmetic or dermatological preparation according toclaim 1.